Innovative technology for fast, simple, and reliable detection of T-cell immunity enables the development of precise diagnostic tests for use in both human and veterinary medicine.
Immunora has developed the IGRA methodology, applied for the FIRST TIME for the diagnosis of bornavirus infection in humans and animals. Based on an innovative "ready-for-use" vial concept with recombinant antigens, it allows precise immunological stimulation of T-cells.
The discovery of a new bornavirus in 2008, which causes the incurable and often fatal disease proventricular dilatation (PDD) in birds. It is widespread worldwide, and the fact that nearly half of bird species migrate contributes to its transmission across regions.
Transmission from animals to humans has already been confirmed — scientific studies in Germany indicate that Borna disease virus 1 (BoDV-1) caused encephalitis in humans. The World Health Organization has recognized bornavirus as a pathogen with pandemic potential, making reliable diagnostic solutions critically important.
Our test, which monitors the T-cell immune response, fills a gap in the existing diagnosis of bornavirus infection and paves the way for understanding immunopathogenesis and the future development of a vaccine — which, even after 17 years, still does not exist.